Vitamin C For High Blood Pressure

Vitamin C is a useful natural remedy for high blood pressure. It is needed for collagen formation which allows blood vessels to function normally and retain their strength and elasticity.

As vitamin C is a water-soluble vitamin, it cannot be stored in the body and a regular intake is essential. Dietary sources include most fruit and vegetables including citrus, berries, blackcurrants, capsicum peppers, kiwi fruit and green leafy vegetables.

Vitamin C for high blood pressure

Vitamin C is an important antioxidant in all body tissues, and is needed for at least 300 metabolic reactions to work properly, including the production of collagen to maintain elastic arteries. It is also involved in the metabolism of stress hormones. New findings suggest that vitamin C is also involved in regulating levels of fibrinogen – a circulating protein that is involved in blood clotting.

Studies show that men and women with the highest dietary intakes of vitamin C have a lower risk of developing high blood pressure, coronary heart disease and stroke.

The results from 29 trials show that taking an average dose of 500mg vitamin C per day for 8 weeks reduced blood pressure by an average of 3.84/1.48 mmHg compared with placebo. However, some of these trials involved people with normal blood pressure. When only trials involving people with high blood pressure were assessed, taking vitamin C was associated with a reduction in blood pressure of 4.85/1.67 mmHg.

You can’t make vitamin C

Most animals make their own vitamin C, but humans and other primates lack the enzyme (L-gulonolactone oxidase) needed for its synthesis. The goat, for example, which weighs around the same as a man, normally produces between 2g and 13g of vitamin C per day and synthesis dramatically increases during times of physical stress and illness.

shutterstock_88357705 (2) lerche&johnsonQuite why humans have either lost, or never acquired the ability to synthesize our vitamin C requirements remains one of the greatest mysteries of human biochemistry. It is thought to have resulted from a genetic accident millions of years ago. This genetic defect also increases the risk of a number of other common illnesses such as viral infections, raised cholesterol levels, coronary heart disease and cancer as well as reducing our ability to cope with stress.

Because our primitive ancestors ate a vegetarian diet full of vitamin C-rich plants such as purslane (just 100 g of which contained 27 mg vitamin C), their vitamin C intake was much higher than is found in the modern diet, and estimated at 392 mg a day. This high dietary intake meant they were able to obtain adequate amounts from their diet.

Vitamin C protects against heart disease

Lack of vitamin C is a risk factor for heart attack and stroke. Data from 15 trials suggest that people with the highest intake of vitamin C, from both diet and supplements, have a 16% lower risk of coronary heart disease than those with the lowest intakes.

A study in Norfolk, UK, involving over 19,000 adults aged 45 to 79 years found that circulating levels of vitamin C were inversely related to death from all causes over the 4 year study period.

The researchers concluded that even relatively small increases in vitamin C concentrations may have a measurable effect on risk of a fatal heart attack; for example, eating an orange a day was estimated to reduce the risk of coronary heart disease by as much as 10%.

Vitamin C dose

The EU RDA for vitamin C is 80 mg. An expert scientific panel in the US have suggested that the intake needed to meet the requirement of half the healthy individuals in a population is 100 mg/day, with a safety margin giving a proposed daily amount of 120 mg/day. The recommendation is 100mg per day in Austria, Germany and Switzerland. The upper safe level for long-term use from supplements is suggested as 1000mg. Higher doses can cause indigestion and have a laxative effect. These are largely due to the acidity of vitamin C itself and are not a sign of toxicity.

If you are prone to indigestion, a non-acidic form of vitamin C, known as ester-C, is best.

Vitamin C safety

If you are taking vitamin C and need to have a urine test inform your doctor that you are taking supplements as it can affect laboratory results.

Some urine test kits used by diabetics are also affected by high dose vitamin C – use a kit that is not affected.

High-dose vitamin C may mask the presence of blood in stool tests – inform your doctor if you are advised to have one of these.

People with iron-storage disease (haemochromatosis) should only take vitamin C supplements under medical advice.

Recurrent stone formers and sufferers of renal failure who have a defect in ascorbic acid or oxalate metabolism, should restrict daily vitamin C intakes to approximately 100 mg.

Anyone who is taking a very high-dose supplement and needs to reduce their vitamin C intake should do this slowly over a few weeks rather than stopping suddenly, in order to avoid a so-called ‘rebound scurvy’ effect. A sudden reduction in blood vitamin C concentration means that enzymes activated by high levels of vitamin C are suddenly deprived of the extra vitamin C they need to work properly, and this can produce temporary symptoms of vitamin C deficiency.

Image credit: miwa-in-oz; lerch&johnson / shutterstock

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